Anti-IKZF4 antibody (471-520 aa) (STJ92930)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human IKZF4 at the amino acid range 471-520
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein Eos (471-520 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IKZF4 |
| Gene ID | 64375 |
| Uniprot ID | IKZF4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human IKZF4 at the amino acid range 471-520 |
| Immunogen Region | 471-520 aa |
| Specificity | Eos Polyclonal Antibody detects endogenous levels of Eos protein. |
Additional Info
| Function | DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1. |
| Protein Name | Zinc Finger Protein EosIkaros Family Zinc Finger Protein 4 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein Eos antibodyAnti-Ikaros Family Zinc Finger Protein 4 antibodyAnti-IKZF4 antibodyAnti-KIAA1782 antibodyAnti-ZNFN1A4 antibody |
Information sourced from Uniprot.org