| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc finger protein Eos (471-520 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IKZF4 |
| Gene ID: |
64375 |
| Uniprot ID: |
IKZF4_HUMAN |
| Immunogen Region: |
471-520 aa |
| Specificity: |
Eos Polyclonal Antibody detects endogenous levels of Eos protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human IKZF4 at the amino acid range 471-520 |
| Function | DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1. |
| Protein Name | Zinc Finger Protein EosIkaros Family Zinc Finger Protein 4 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein Eos antibodyAnti-Ikaros Family Zinc Finger Protein 4 antibodyAnti-IKZF4 antibodyAnti-KIAA1782 antibodyAnti-ZNFN1A4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
