Anti-IKBIP antibody (STJA0004538)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human IKBIP
General Information
| Short Description | Rabbit polyclonal anti-Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | IKBIP |
| Gene ID | 121457 |
| Uniprot ID | IKIP_HUMAN |
| Immunogen | Recombinant protein of human IKBIP |
Additional Info
| Tissue Specificity | Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. |
| Post Translational Modifications | N-glycosylated. Isoform 4 is glycosylated at Asn-154. |
| Function | Target of p53/TP53 with pro-apoptotic function. |
| Protein Name | Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting ProteinI Kappa-B Kinase-Interacting ProteinIkbkb-Interacting ProteinIkk-Interacting Protein |
| Database Links | Reactome: R-HSA-9758274 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIsoform 4 Deletion Of The HydrophobicOr Transmembrane Region Between Aa 45-63 Results In Uniform Distribution Throughout The CellSuggesting That This Region Is Responsible For Endoplasmic Reticulum Localization |
| Alternative Antibody Names | Anti-Inhibitor Of Nuclear Factor Kappa-B Kinase-Interacting Protein antibodyAnti-I Kappa-B Kinase-Interacting Protein antibodyAnti-Ikbkb-Interacting Protein antibodyAnti-Ikk-Interacting Protein antibodyAnti-IKBIP antibodyAnti-IKIP antibody |
Information sourced from Uniprot.org