Immunohistochemistry analysis of IGHMBP2 in paraffin-embedded mouse liver using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-IGHMBP2 antibody (540-720) (STJ118494)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ118494
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General Information

Short DescriptionRabbit polyclonal IGHMBP2 (540-720) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IHC-P:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolIGHMBP2
Gene ID3508
Uniprot IDSMBP2_HUMAN
Immunogen Region540-720
Immunogen SequencePYNLQVDLLRQSLVHRHPEL EIKSVDGFQGREKEAVILSF VRSNRKGEVGFLAEDRRINV AVTRARRHVAVICDSRTVNN HAFLKTLVEYFTQHGEVRTA FEYLDDIVPENYSHENSQGS SHAATKPQGPATSTRTGSQR QEGGQEAAAPARQGRKKPAG KSLASEAPSQPSLNGGSPEG V
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human IGHMBP2 (NP_002171.2).

Additional Info

Tissue Specificity Expressed in all tissues examined. Expressed in the developing and adult human brain, with highest expression in the cerebellum. Moderately expressed in fibroblasts.
Function 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.
Protein Name Dna-Binding Protein Smubp-2
Atp-Dependent Helicase Ighmbp2
Glial Factor 1
Gf-1
Immunoglobulin Mu-Binding Protein 2
Database Links
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Axon
Alternative Antibody Names Anti-Dna-Binding Protein Smubp-2 antibody
Anti-Atp-Dependent Helicase Ighmbp2 antibody
Anti-Glial Factor 1 antibody
Anti-Gf-1 antibody
Anti-Immunoglobulin Mu-Binding Protein 2 antibody
Anti-IGHMBP2 antibody
Anti-SMBP2 antibody
Anti-SMUBP2 antibody

Information sourced from Uniprot.org

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