Anti-IGFBP7 antibody (50-150) [S7MR] (STJ11102117)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal IGFBP7 (50-150) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IGFBP7 |
| Gene ID | 3490 |
| Uniprot ID | IBP7_HUMAN |
| Immunogen Region | 50-150 |
| Immunogen Sequence | LGETRDACGCCPMCARGEGE PCGGGGAGRGYCAPGMECVK SRKRRKGKAGAAAGGPGVSG VCVCKSRYPVCGSDGTTYPS GCQLRAASQRAESRGEKAIT Q |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IGFBP7 (Q16270). |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin-Like Growth Factor-Binding Protein 7 antibodyAnti-Ibp-7 antibodyAnti-Igf-Binding Protein 7 antibodyAnti-Igfbp-7 antibodyAnti-Igfbp-Rp1 antibodyAnti-Mac25 Protein antibodyAnti-Pgi2-Stimulating Factor antibodyAnti-Prostacyclin-Stimulating Factor antibodyAnti-Tumor-Derived Adhesion Factor antibodyAnti-Taf antibodyAnti-IGFBP7 antibodyAnti-MAC25 antibodyAnti-PSF antibody |
Information sourced from Uniprot.org