Anti-IGFBP7 antibody (27-282) (STJ114990)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IGFBP7 (27-282) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IGFBP7 |
| Gene ID | 3490 |
| Uniprot ID | IBP7_HUMAN |
| Immunogen Region | 27-282 |
| Immunogen Sequence | SSSDTCGPCEPASCPPLPPL GCLLGETRDACGCCPMCARG EGEPCGGGGAGRGYCAPGME CVKSRKRRKGKAGAAAGGPG VSGVCVCKSRYPVCGSDGTT YPSGCQLRAASQRAESRGEK AITQVSKGTCEQGPSIVTPP KDIWNVTGAQVYLSCEVIGI PTPVLIWNKVKRGHYGVQRT ELLPGDRDNLAIQTRGGPEK HEVTGWVLVSPLSKEDAGEY ECHASNSQGQASASAKITV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_001544.1). |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin-Like Growth Factor-Binding Protein 7 antibodyAnti-Ibp-7 antibodyAnti-Igf-Binding Protein 7 antibodyAnti-Igfbp-7 antibodyAnti-Igfbp-Rp1 antibodyAnti-Mac25 Protein antibodyAnti-Pgi2-Stimulating Factor antibodyAnti-Prostacyclin-Stimulating Factor antibodyAnti-Tumor-Derived Adhesion Factor antibodyAnti-Taf antibodyAnti-IGFBP7 antibodyAnti-MAC25 antibodyAnti-PSF antibody |
Information sourced from Uniprot.org