• Anti-IgE antibody [4H10+] (STJ16101392)

Anti-IgE antibody [4H10+] (STJ16101392)

SKU:
STJ16101392-01

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Host: Mouse
Applications: FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-IgE is suitable for use in Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 4H10+
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification: Purified by protein-A affinity chromatography.
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Purified human IgE.
Background Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days) , it is stabilized after binding to its high affinity receptor. Unlike IgM-IgG-and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.

Information sourced from Uniprot.org

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