Anti-IGBP1 antibody (STJA0009566)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human IGBP1
General Information
| Short Description | Rabbit polyclonal anti-Immunoglobulin-binding protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IGBP1 |
| Gene ID | 3476 |
| Uniprot ID | IGBP1_HUMAN |
| Immunogen | Synthesized peptide derived from human IGBP1 |
| Specificity | This antibody detects endogenous levels of IGBP1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated. Monoubiquitination by MID1 triggers calpain-mediated cleavage and switches IGBP1 activity from protective to destructive. |
| Function | Associated to surface IgM-receptor.may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits. |
| Protein Name | Immunoglobulin-Binding Protein 1B-Cell Signal Transduction Molecule Alpha 4Protein Alpha-4Cd79a-Binding Protein 1Protein Phosphatase 2/4/6 Regulatory SubunitRenal Carcinoma Antigen Ny-Ren-16 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Immunoglobulin-Binding Protein 1 antibodyAnti-B-Cell Signal Transduction Molecule Alpha 4 antibodyAnti-Protein Alpha-4 antibodyAnti-Cd79a-Binding Protein 1 antibodyAnti-Protein Phosphatase 2/4/6 Regulatory Subunit antibodyAnti-Renal Carcinoma Antigen Ny-Ren-16 antibodyAnti-IGBP1 antibodyAnti-IBP1 antibody |
Information sourced from Uniprot.org