| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IGBP1 (1-339) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IGBP1 |
| Gene ID: |
3476 |
| Uniprot ID: |
IGBP1_HUMAN |
| Immunogen Region: |
1-339 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human IGBP1 (NP_001542.1). |
| Immunogen Sequence: |
MAAEDELQLPRLPELFETGR QLLDEVEVATEPAGSRIVQE KVFKGLDLLEKAAEMLSQLD LFSRNEDLEEIASTDLKYLL VPAFQGALTMKQVNPSKRLD HLQRAREHFINYLTQCHCYH VAEFELPKTMNNSAENHTAN SSMAYPSLVAMASQRQAKIQ RYKQKKELEHRLSAMKSAVE SGQADDERVREYYLLHLQRW IDISLEEIESIDQEIKILRE RDSSREASTSNSSRQERPP |
| Tissue Specificity | Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas. |
| Post Translational Modifications | Phosphorylated. Monoubiquitination by MID1 triggers calpain-mediated cleavage and switches IGBP1 activity from protective to destructive. |
| Function | Associated to surface IgM-receptor.may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits. |
| Protein Name | Immunoglobulin-Binding Protein 1B-Cell Signal Transduction Molecule Alpha 4Protein Alpha-4Cd79a-Binding Protein 1Protein Phosphatase 2/4/6 Regulatory SubunitRenal Carcinoma Antigen Ny-Ren-16 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Immunoglobulin-Binding Protein 1 antibodyAnti-B-Cell Signal Transduction Molecule Alpha 4 antibodyAnti-Protein Alpha-4 antibodyAnti-Cd79a-Binding Protein 1 antibodyAnti-Protein Phosphatase 2/4/6 Regulatory Subunit antibodyAnti-Renal Carcinoma Antigen Ny-Ren-16 antibodyAnti-IGBP1 antibodyAnti-IBP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
