Anti-IFT81 antibody (550-676) (STJ116254)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IFT81 (550-676) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IFT81 |
| Gene ID | 28981 |
| Uniprot ID | IFT81_HUMAN |
| Immunogen Region | 550-676 |
| Immunogen Sequence | VRRLREECLQEESRYHYTNC MIKNLEVQLRRATDEMKAYI SSDQQEKRKAIREQYTKNTA EQENLGKKLREKQKVIRESH GPNMKQAKMWRDLEQLMECK KQCFLKQQSQTSIGQVIQEG GEDRLIL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 550-676 of human IFT81 (NP_054774.2). |
Additional Info
| Tissue Specificity | Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. |
| Function | Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella. |
| Protein Name | Intraflagellar Transport Protein 81 HomologCarnitine Deficiency-Associated Protein Expressed In Ventricle 1Cdv-1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonCilium Basal Body |
| Alternative Antibody Names | Anti-Intraflagellar Transport Protein 81 Homolog antibodyAnti-Carnitine Deficiency-Associated Protein Expressed In Ventricle 1 antibodyAnti-Cdv-1 antibodyAnti-IFT81 antibodyAnti-CDV1 antibody |
Information sourced from Uniprot.org