Anti-IFT74 antibody (STJA0008376)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human IFT74
General Information
| Short Description | Rabbit polyclonal anti-Intraflagellar transport protein 74 homolog for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IFT74 |
| Gene ID | 80173 |
| Uniprot ID | IFT74_HUMAN |
| Immunogen | Synthesized peptide derived from human IFT74 |
| Specificity | This antibody detects endogenous levels of IFT74 at Human, Mouse |
Additional Info
| Function | Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. Essential for flagellogenesis during spermatogenesis. |
| Protein Name | Intraflagellar Transport Protein 74 HomologCapillary Morphogenesis Gene 1 ProteinCmg-1Coiled-Coil Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmic VesicleFlagellumSecretory VesicleAcrosomeLocalizes Along Primary Cilia At Interphase And Around The Basal Body/Centriole At Interphase And MitosisIn Male Germ CellsStrongly Expressed In The Vesicles Of Spermatocytes And Round Spermatids And Also In The Acrosome And Centrosome Regions Of Elongating Spermatids And In Developing Sperm Tails |
| Alternative Antibody Names | Anti-Intraflagellar Transport Protein 74 Homolog antibodyAnti-Capillary Morphogenesis Gene 1 Protein antibodyAnti-Cmg-1 antibodyAnti-Coiled-Coil Domain-Containing Protein 2 antibodyAnti-IFT74 antibodyAnti-CCDC2 antibodyAnti-CMG1 antibody |
Information sourced from Uniprot.org