Anti-IFNGR2 antibody [SAA2103] (STJA0027872)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal Interferon Gamma Receptor 2 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA2103 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | IFNGR2 |
| Gene ID | 3460 |
| Uniprot ID | INGR2_HUMAN |
Additional Info
| Function | Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. |
| Protein Name | Interferon Gamma Receptor 2Ifn-Gamma Receptor 2Ifn-Gamma-R2Interferon Gamma Receptor Accessory Factor 1Af-1Interferon Gamma Receptor Beta-ChainIfn-Gamma-R-BetaInterferon Gamma Transducer 1 |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-877312Reactome: R-HSA-9679191Reactome: R-HSA-9732724 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic Vesicle MembraneGolgi Apparatus MembraneEndoplasmic Reticulum MembraneCytoplasmHas Low Cell Surface Expression And High Cytoplasmic Expression In T CellsThe Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling |
| Alternative Antibody Names | Anti-Interferon Gamma Receptor 2 antibodyAnti-Ifn-Gamma Receptor 2 antibodyAnti-Ifn-Gamma-R2 antibodyAnti-Interferon Gamma Receptor Accessory Factor 1 antibodyAnti-Af-1 antibodyAnti-Interferon Gamma Receptor Beta-Chain antibodyAnti-Ifn-Gamma-R-Beta antibodyAnti-Interferon Gamma Transducer 1 antibodyAnti-IFNGR2 antibodyAnti-IFNGT1 antibody |
Information sourced from Uniprot.org