| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Interferon gamma receptor 2 (250-330 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IFNGR2 |
| Gene ID: |
3460 |
| Uniprot ID: |
INGR2_HUMAN |
| Immunogen Region: |
250-330 aa |
| Specificity: |
INGR2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 250-330 |
| Function | Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. |
| Protein Name | Interferon Gamma Receptor 2Ifn-Gamma Receptor 2Ifn-Gamma-R2Interferon Gamma Receptor Accessory Factor 1Af-1Interferon Gamma Receptor Beta-ChainIfn-Gamma-R-BetaInterferon Gamma Transducer 1 |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-877312Reactome: R-HSA-9679191Reactome: R-HSA-9732724 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic Vesicle MembraneGolgi Apparatus MembraneEndoplasmic Reticulum MembraneCytoplasmHas Low Cell Surface Expression And High Cytoplasmic Expression In T CellsThe Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling |
| Alternative Antibody Names | Anti-Interferon Gamma Receptor 2 antibodyAnti-Ifn-Gamma Receptor 2 antibodyAnti-Ifn-Gamma-R2 antibodyAnti-Interferon Gamma Receptor Accessory Factor 1 antibodyAnti-Af-1 antibodyAnti-Interferon Gamma Receptor Beta-Chain antibodyAnti-Ifn-Gamma-R-Beta antibodyAnti-Interferon Gamma Transducer 1 antibodyAnti-IFNGR2 antibodyAnti-IFNGT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
