Anti-IFI30 antibody (3-53 aa) (STJ193466)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human IFI30 at the amino acid range 3-53
General Information
| Short Description | Rabbit polyclonal anti-Gamma-interferon-inducible lysosomal thiol reductase (3-53 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IFI30 |
| Gene ID | 10437 |
| Uniprot ID | GILT_HUMAN |
| Immunogen | Synthesized peptide derived from the human IFI30 at the amino acid range 3-53 |
| Immunogen Region | 3-53 aa |
| Specificity | This antibody detects endogenous levels of IFI30 at Human/Mouse/Rat |
Additional Info
| Function | Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation. |
| Protein Name | Gamma-Interferon-Inducible Lysosomal Thiol ReductaseGamma-Interferon-Inducible Protein Ip-30Legumaturain |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-877300 |
| Cellular Localisation | SecretedLysosome |
| Alternative Antibody Names | Anti-Gamma-Interferon-Inducible Lysosomal Thiol Reductase antibodyAnti-Gamma-Interferon-Inducible Protein Ip-30 antibodyAnti-Legumaturain antibodyAnti-IFI30 antibodyAnti-GILT antibodyAnti-IP30 antibody |
Information sourced from Uniprot.org