| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Iduronate 2-sulfatase is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IDS |
| Gene ID: |
3423 |
| Uniprot ID: |
IDS_HUMAN |
| Specificity: |
IDS Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. |
| Protein Name | Iduronate 2-SulfataseAlpha-L-Iduronate Sulfate SulfataseIdursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain |
| Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2024101Reactome: R-HSA-2206296 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Iduronate 2-Sulfatase antibodyAnti-Alpha-L-Iduronate Sulfate Sulfatase antibodyAnti-Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain antibodyAnti-IDS antibodyAnti-SIDS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
