Anti-IDH2 antibody [R01-7E4] (STJA0034452)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human IDH2
General Information
| Short Description | Rabbit monoclonal anti-IDH2 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-7E4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IDH2 |
| Gene ID | 3418 |
| Uniprot ID | IDHP_HUMAN |
| Immunogen | A synthetic peptide of human IDH2 |
Additional Info
| Post Translational Modifications | Acetylation at Lys-413 dramatically reduces catalytic activity. Deacetylated by SIRT3. |
| Function | Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. |
| Protein Name | Isocitrate Dehydrogenase Nadp - MitochondrialIdhIcd-MIdpNadp(+-Specific IcdhOxalosuccinate Decarboxylase |
| Database Links | Reactome: R-HSA-2151201Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Isocitrate Dehydrogenase Nadp - Mitochondrial antibodyAnti-Idh antibodyAnti-Icd-M antibodyAnti-Idp antibodyAnti-Nadp(+-Specific Icdh antibodyAnti-Oxalosuccinate Decarboxylase antibodyAnti-IDH2 antibody |
Information sourced from Uniprot.org