Anti-ID3 antibody (68-117 aa) (STJ192556)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 68-117
General Information
| Short Description | Rabbit polyclonal anti-DNA-binding protein inhibitor ID-3 (68-117 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ID3 |
| Gene ID | 3399 |
| Uniprot ID | ID3_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 68-117 |
| Immunogen Region | 68-117 aa |
| Specificity | ID3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. |
| Protein Name | Dna-Binding Protein Inhibitor Id-3Class B Basic Helix-Loop-Helix Protein 25Bhlhb25Helix-Loop-Helix Protein Heir-1Id-Like Protein Inhibitor Hlh 1r21Inhibitor Of Dna Binding 3Inhibitor Of Differentiation 3 |
| Database Links | Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna-Binding Protein Inhibitor Id-3 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 25 antibodyAnti-Bhlhb25 antibodyAnti-Helix-Loop-Helix Protein Heir-1 antibodyAnti-Id-Like Protein Inhibitor Hlh 1r21 antibodyAnti-Inhibitor Of Dna Binding 3 antibodyAnti-Inhibitor Of Differentiation 3 antibodyAnti-ID3 antibodyAnti-1R21 antibodyAnti-BHLHB25 antibodyAnti-HEIR1 antibody |
Information sourced from Uniprot.org