| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNA-binding protein inhibitor ID-3 (68-117 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ID3 |
| Gene ID: |
3399 |
| Uniprot ID: |
ID3_HUMAN |
| Immunogen Region: |
68-117 aa |
| Specificity: |
ID3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 68-117 |
| Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. |
| Protein Name | Dna-Binding Protein Inhibitor Id-3Class B Basic Helix-Loop-Helix Protein 25Bhlhb25Helix-Loop-Helix Protein Heir-1Id-Like Protein Inhibitor Hlh 1r21Inhibitor Of Dna Binding 3Inhibitor Of Differentiation 3 |
| Database Links | Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna-Binding Protein Inhibitor Id-3 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 25 antibodyAnti-Bhlhb25 antibodyAnti-Helix-Loop-Helix Protein Heir-1 antibodyAnti-Id-Like Protein Inhibitor Hlh 1r21 antibodyAnti-Inhibitor Of Dna Binding 3 antibodyAnti-Inhibitor Of Differentiation 3 antibodyAnti-ID3 antibodyAnti-1R21 antibodyAnti-BHLHB25 antibodyAnti-HEIR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
