Anti-ICAM4 antibody (169-182) (STJ72932)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-ICAM4 (169-182) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 28kDa band observed in Human Umbillical Cord and in Erythrocytes lysates (calculated MW of 29.3kDa according to NP_001535.1). Recommended concentration: 1-3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ICAM4 |
| Gene ID | 3386 |
| Uniprot ID | ICAM4_HUMAN |
| Accession Number | NP_001535.1; NP_071772.1 |
| Immunogen Region | 169-182 |
| Immunogen Sequence | RHGSRVIYSESLER |
| Specificity | This antibody is expected to recognize isoform 1 (NP_001535.1) and isoform 2 (NP_071772.1) only. |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. |
| Protein Name | Intercellular Adhesion Molecule 4Icam-4Landsteiner-Wiener Blood Group GlycoproteinLw Blood Group ProteinCd Antigen Cd242 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083 |
| Cellular Localisation | Isoform Long: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Short: SecretedCell Membrane |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 4 antibodyAnti-Icam-4 antibodyAnti-Landsteiner-Wiener Blood Group Glycoprotein antibodyAnti-Lw Blood Group Protein antibodyAnti-Cd Antigen Cd242 antibodyAnti-ICAM4 antibodyAnti-LW antibody |
Information sourced from Uniprot.org