Anti-ICAM2/CD102 antibody (1-240) [S4089RM] (STJ11104089)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal ICAM2/CD102 (1-240) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4089RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Icam2 |
| Gene ID | 15896 |
| Uniprot ID | ICAM2_MOUSE |
| Immunogen Region | 1-240 |
| Immunogen Sequence | MSSFACWSLSLLILFYSPGS GEKAFEVYIWSEKQIVEATE SWKINCSTNCAAPDMGGLET PTNKIMLEEHPQGKWKQFLV SNVSKDTVFFCHFTCSGKQH SESLNIRVYQPPAQVTLKLQ PPRVFVGEDFTIECTVSPVQ PLERLTLSLLRGRETLKNQT FGGAETVPQEATATFNSTAL KKDGLNFSCQAELDLRPHGG YIIRSISEYQILEVYEPMQD NQMVIIIVVVSILLFLFVT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of mouse ICAM2/CD102 (P35330). |
Additional Info
| Tissue Specificity | Expressed in endothelial cells and leukocytes. High levels found in lung. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
| Protein Name | Intercellular Adhesion Molecule 2Icam-2Lymphocyte Function-Associated Ag-1 Counter-ReceptorCd Antigen Cd102 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083Reactome: -MMU-5621575 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Lymphocyte Function-Associated Ag-1 Counter-Receptor antibodyAnti-Cd Antigen Cd102 antibodyAnti-Icam2 antibodyAnti-Icam-2 antibody |
Information sourced from Uniprot.org