Anti-Icam2 antibody (23-222 aa) [R06-7A3] (STJA0012421)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of mouse ICAM2
General Information
| Short Description | Rabbit monoclonal anti-ICAM2 (23-222 aa) for use in WB, IHC-P and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7A3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4ยฐC short term. Aliquot and store at-20ยฐC long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | Icam2 |
| Gene ID | 15896 |
| Uniprot ID | ICAM2_MOUSE |
| Immunogen | Recombinant protein of mouse ICAM2 |
| Immunogen Region | 23-222 aa |
Additional Info
| Tissue Specificity | Expressed in endothelial cells and leukocytes. High levels found in lung. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
| Protein Name | Intercellular Adhesion Molecule 2Icam-2Lymphocyte Function-Associated Ag-1 Counter-ReceptorCd Antigen Cd102 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083Reactome: -MMU-5621575 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Lymphocyte Function-Associated Ag-1 Counter-Receptor antibodyAnti-Cd Antigen Cd102 antibodyAnti-Icam2 antibodyAnti-Icam-2 antibody |
Information sourced from Uniprot.org