Anti-ICAM-1 antibody [MEM-111] (STJ16100956)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenRaji human Burkitt's lymphoma cell line
General Information
| Short Description | Mouse monoclonal anti-CD54 for use in FC in Human, Cow and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human/Cow/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MEM-111 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Formulation | Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Raji human Burkitt's lymphoma cell line |
Additional Info
| Background | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B-and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Information sourced from Uniprot.org