Anti-ICAM-1 antibody [MEM 111] (STJ16100067)

Anti-ICAM-1 antibody [MEM 111] (STJ16100067)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenRaji human Burkitt's lymphoma cell line
STJ16100067-01
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General Information

Short DescriptionMouse monoclonal anti-CD54 for use in WB, IHC-P, ELISA, FC and ICC in Human, Cow and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA/FC/ICC
HostMouse
ReactivityHuman/Cow/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDMEM 111
IsotypeIgG2a
ConjugationUnconjugated
Concentration1 mg/mL
FormulationPhosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenRaji human Burkitt's lymphoma cell line

Additional Info

Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B-and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.

Information sourced from Uniprot.org

Citations

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