| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inhibitor of Bruton tyrosine kinase (410-490 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IBTK |
| Gene ID: |
25998 |
| Uniprot ID: |
IBTK_HUMAN |
| Immunogen Region: |
410-490 aa |
| Specificity: |
IBTK Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 410-490 |
| Function | Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription. |
| Protein Name | Inhibitor Of Bruton Tyrosine KinaseIbtk |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinTranslocates To The Plasma Membrane Upon Igm StimulationIsoform 2: Nucleus |
| Alternative Antibody Names | Anti-Inhibitor Of Bruton Tyrosine Kinase antibodyAnti-Ibtk antibodyAnti-IBTK antibodyAnti-BTKI antibodyAnti-KIAA1417 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
