Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Bone Sialoprotein 2 (1-100) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
IBSP |
Gene ID: |
3381 |
Uniprot ID: |
SIAL_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IBSP (NP_004958.2). |
Immunogen Sequence: |
MKTALILLSILGMACAFSMK NLHRRVKIEDSEENGVFKYR PRYYLYKHAYFYPHLKRFPV QGSSDSSEENGDDSSEEEEE EEETSNEGENNEESNEDEDS |
Post Translational Modifications | N-glycosylated.glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains. O-glycosylated at eight sites.mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc. Sulfated on either Tyr-313 or Tyr-314. |
Function | Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. |
Protein Name | Bone Sialoprotein 2Bone Sialoprotein IiBsp IiCell-Binding SialoproteinIntegrin-Binding Sialoprotein |
Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000178 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Bone Sialoprotein 2 antibodyAnti-Bone Sialoprotein Ii antibodyAnti-Bsp Ii antibodyAnti-Cell-Binding Sialoprotein antibodyAnti-Integrin-Binding Sialoprotein antibodyAnti-IBSP antibodyAnti-BNSP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance