Anti-IARS antibody (1158-1262) (STJ112228)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IARS (1158-1262) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IARS1 |
| Gene ID | 3376 |
| Uniprot ID | SYIC_HUMAN |
| Immunogen Region | 1158-1262 |
| Immunogen Sequence | SAPSLINSSSTLLCQYINLQ LLNAKPQECLMGTVGTLLLE NPLGQNGLTHQGLLYEAAKV FGLRSRKLKLFLNETQTQEI TEDIPVKTLNMKTVYVSVLP TTADF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1158-1262 of human IARS (NP_002152.2). |
Additional Info
| Tissue Specificity | Expressed in liver and muscle (at protein level). |
| Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. |
| Protein Name | Isoleucine--Trna Ligase - CytoplasmicIsoleucyl-Trna SynthetaseIrsIlers |
| Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Isoleucine--Trna Ligase - Cytoplasmic antibodyAnti-Isoleucyl-Trna Synthetase antibodyAnti-Irs antibodyAnti-Ilers antibodyAnti-IARS1 antibodyAnti-IARS antibody |
Information sourced from Uniprot.org