Anti-IAPP antibody [SAA0538] (STJA0019372)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Islet Amyloid Polypeptide antibody for use in ELISA and IHC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0538 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | IAPP |
| Gene ID | 3375 |
| Uniprot ID | IAPP_HUMAN |
Additional Info
| Function | Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs. |
| Protein Name | Islet Amyloid PolypeptideIappAmylinDiabetes-Associated PeptideDapInsulinoma Amyloid Peptide |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-418555Reactome: R-HSA-419812Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Islet Amyloid Polypeptide antibodyAnti-Iapp antibodyAnti-Amylin antibodyAnti-Diabetes-Associated Peptide antibodyAnti-Dap antibodyAnti-Insulinoma Amyloid Peptide antibodyAnti-IAPP antibody |
Information sourced from Uniprot.org