| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Voltage-gated hydrogen channel 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HVCN1 |
| Gene ID: |
84329 |
| Uniprot ID: |
HVCN1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HVCN1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human HVCN1 |
| Post Translational Modifications | Phosphorylation may enhance channel gating. |
| Function | Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. |
| Protein Name | Voltage-Gated Hydrogen Channel 1Hydrogen Voltage-Gated Channel 1Hv1Voltage Sensor Domain-Only Protein |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1300642Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneDetected Mainly At Intracellular Membranes Upon Overexpression In Hela CellsBut Not In Other Cell Types |
| Alternative Antibody Names | Anti-Voltage-Gated Hydrogen Channel 1 antibodyAnti-Hydrogen Voltage-Gated Channel 1 antibodyAnti-Hv1 antibodyAnti-Voltage Sensor Domain-Only Protein antibodyAnti-HVCN1 antibodyAnti-VSOP antibodyAnti-UNQ578 antibodyAnti-PRO1140 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
