Anti-Human Serum Albumin antibody [1A8-C5-B4] (STJA0033187)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified Human serum albumin.
STJA0033187
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General Information

Short DescriptionMouse monoclonal anti-Human Serum Albumin for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID1A8-C5-B4
IsotypeIgG1
ConjugationUnconjugated
Concentration5.7 mg/mL
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
ELISA 1:10000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolALB
Gene ID213
Uniprot IDALBU_HUMAN
ImmunogenPurified Human serum albumin.

Additional Info

Tissue Specificity Plasma.
Post Translational Modifications Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylated by FAM20C in the extracellular medium. Acetylated on Lys-223 by acetylsalicylic acid.
Function Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.
Protein Name Albumin
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-159418
Reactome: R-HSA-189451
Reactome: R-HSA-189483
Reactome: R-HSA-2168880
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-8964058
Reactome: R-HSA-9707564
Reactome: R-HSA-9749641
Reactome: R-HSA-9757110
Reactome: R-HSA-9793528
Cellular Localisation Secreted
Alternative Antibody Names Anti-Albumin antibody
Anti-ALB antibody
Anti-GIG20 antibody
Anti-GIG42 antibody
Anti-PRO0903 antibody
Anti-PRO1708 antibody
Anti-PRO2044 antibody
Anti-PRO2619 antibody
Anti-PRO2675 antibody
Anti-UNQ696 antibody
Anti-PRO1341 antibody

Information sourced from Uniprot.org

Citations

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