• Western blot analysis of lysates from HepG2 and Jurkat cells, using 5-HT-1A Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using SR-1A Polyclonal Antibody diluted at 1:500

Anti-HTR1A antibody (291-340 aa) (STJ95756)

SKU:
STJ95756

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 1A (291-340 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HTR1A
Gene ID: 3350
Uniprot ID: 5HT1A_HUMAN
Immunogen Region: 291-340 aa
Specificity: SR-1A Polyclonal Antibody detects endogenous levels of SR-1A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human 5-HT-1A at the amino acid range 291-340
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Protein Name 5-Hydroxytryptamine Receptor 1a
5-Ht-1a
5-Ht1a
G-21
Serotonin Receptor 1a
Database Links Reactome: R-HSA-390666
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Dendrite
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 1a antibody
Anti-5-Ht-1a antibody
Anti-5-Ht1a antibody
Anti-G-21 antibody
Anti-Serotonin Receptor 1a antibody
Anti-HTR1A antibody
Anti-ADRB2RL1 antibody
Anti-ADRBRL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance