Anti-HSPB8 antibody [2C3] (STJ97543)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecombinant Protein of HSPB8/HSP22
General Information
| Short Description | Mouse monoclonal anti-Heat shock protein beta-8 for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2C3 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSPB8 |
| Gene ID | 26353 |
| Uniprot ID | HSPB8_HUMAN |
| Immunogen | Recombinant Protein of HSPB8/HSP22 |
| Specificity | HSPB8/HSP22 protein detects endogenous levels of HSPB8/HSP22 |
Additional Info
| Function | Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8Hspb8Alpha-Crystallin C ChainE2-Induced Gene 1 ProteinHeat Shock Protein Family B Member 8Protein Kinase H11Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | CytoplasmNucleusTranslocates To Nuclear Foci During Heat Shock |
| Alternative Antibody Names | Anti-Heat Shock Protein Beta-8 antibodyAnti-Hspb8 antibodyAnti-Alpha-Crystallin C Chain antibodyAnti-E2-Induced Gene 1 Protein antibodyAnti-Heat Shock Protein Family B Member 8 antibodyAnti-Protein Kinase H11 antibodyAnti-Small Stress Protein-Like Protein Hsp22 antibodyAnti-HSPB8 antibodyAnti-CRYAC antibodyAnti-E2IG1 antibodyAnti-HSP22 antibodyAnti-PP1629 antibody |
Information sourced from Uniprot.org