Anti-HSPB8 antibody (1-100) [S4MR] (STJ11101424)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal HSPB8/HSP22 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSPB8 |
| Gene ID | 26353 |
| Uniprot ID | HSPB8_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MADGQMPFSCHYPSRLRRDP FRDSPLSSRLLDDGFGMDPF PDDLTASWPDWALPRLSSAW PGTLRSGMVPRGPTATARFG VPAEGRTPPPFPGEPWKVCV |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HSPB8/HSP22 (Q9UJY1). |
Additional Info
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart. |
| Function | Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8Hspb8Alpha-Crystallin C ChainE2-Induced Gene 1 ProteinHeat Shock Protein Family B Member 8Protein Kinase H11Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | CytoplasmNucleusTranslocates To Nuclear Foci During Heat Shock |
| Alternative Antibody Names | Anti-Heat Shock Protein Beta-8 antibodyAnti-Hspb8 antibodyAnti-Alpha-Crystallin C Chain antibodyAnti-E2-Induced Gene 1 Protein antibodyAnti-Heat Shock Protein Family B Member 8 antibodyAnti-Protein Kinase H11 antibodyAnti-Small Stress Protein-Like Protein Hsp22 antibodyAnti-HSPB8 antibodyAnti-CRYAC antibodyAnti-E2IG1 antibodyAnti-HSP22 antibodyAnti-PP1629 antibody |
Information sourced from Uniprot.org