Anti-HSP40/DNAJB1 antibody (1-340aa) [k1C7] (STJA0041504)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human Hsp40 (1-340aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-HSP40/DNAJB1 (1-340aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | k1C7 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAJB1 |
| Gene ID | 3337 |
| Uniprot ID | DNJB1_HUMAN |
| Accession Number | NM_006145 |
| Immunogen | Recombinant human Hsp40 (1-340aa) purified from E. coli |
| Immunogen Region | 1-340aa |
Additional Info
| Function | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). |
| Protein Name | Dnaj Homolog Subfamily B Member 1Dnaj Protein Homolog 1Heat Shock 40 Kda Protein 1Hsp40Heat Shock Protein 40Human Dnaj Protein 1Hdj-1 |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-3371497Reactome: R-HSA-3371568Reactome: R-HSA-3371571Reactome: R-HSA-5687128 |
| Cellular Localisation | CytoplasmNucleusNucleolusTranslocates Rapidly From The Cytoplasm To The NucleusAnd Especially To The NucleoliUpon Heat Shock |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily B Member 1 antibodyAnti-Dnaj Protein Homolog 1 antibodyAnti-Heat Shock 40 Kda Protein 1 antibodyAnti-Hsp40 antibodyAnti-Heat Shock Protein 40 antibodyAnti-Human Dnaj Protein 1 antibodyAnti-Hdj-1 antibodyAnti-DNAJB1 antibodyAnti-DNAJ1 antibodyAnti-HDJ1 antibodyAnti-HSPF1 antibody |
Information sourced from Uniprot.org