Anti-HSH2D antibody (Internal) (STJ72179)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HSH2D (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 37kDa band observed in lysates of cell line K562 (calculated MW of 39.0kDa according to NP_116244.1). Recommended concentration: 0.3-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HSH2D |
| Gene ID | 84941 |
| Uniprot ID | HSH2D_HUMAN |
| Accession Number | NP_116244.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | HSHVGYTLSYKAQ |
Additional Info
| Post Translational Modifications | May be phosphorylated by FES and ACK1. |
| Function | May be a modulator of the apoptotic response through its ability to affect mitochondrial stability. Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. |
| Protein Name | Hematopoietic Sh2 Domain-Containing ProteinHematopoietic Sh2 ProteinAdaptor In Lymphocytes Of Unknown Function X |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Hematopoietic Sh2 Domain-Containing Protein antibodyAnti-Hematopoietic Sh2 Protein antibodyAnti-Adaptor In Lymphocytes Of Unknown Function X antibodyAnti-HSH2D antibodyAnti-ALX antibody |
Information sourced from Uniprot.org