| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-HSH2D (325-339) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Preliminary experiments in Human Spleen, Tonsil, and Lymph Node lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feed |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HSH2D |
| Gene ID: | 84941 |
| Uniprot ID: | HSH2D_HUMAN |
| Immunogen Region: | 325-339 |
| Accession Number: | NP_116244.1 |
| Immunogen Sequence: | EHQGLAEPENDQLPE |
| Post Translational Modifications | May be phosphorylated by FES and ACK1. |
| Function | May be a modulator of the apoptotic response through its ability to affect mitochondrial stability. Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. |
| Protein Name | Hematopoietic Sh2 Domain-Containing ProteinHematopoietic Sh2 ProteinAdaptor In Lymphocytes Of Unknown Function X |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Hematopoietic Sh2 Domain-Containing Protein antibodyAnti-Hematopoietic Sh2 Protein antibodyAnti-Adaptor In Lymphocytes Of Unknown Function X antibodyAnti-HSH2D antibodyAnti-ALX antibody |
Information sourced from Uniprot.org