| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-17-beta-hydroxysteroid dehydrogenase type 6 (28-78 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HSD17B6 |
| Gene ID: |
8630 |
| Uniprot ID: |
H17B6_HUMAN |
| Immunogen Region: |
28-78 aa |
| Specificity: |
This antibody detects endogenous levels of H17B6 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human H17B6 at the amino acid range 28-78 |
| Function | NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 617-Beta-Hsd 617-Beta-Hsd6 3-Alpha->Beta-Hydroxysteroid Epimerase3-Alpha->Beta-HseOxidative 3-Alpha Hydroxysteroid DehydrogenaseShort Chain Dehydrogenase/Reductase Family 9c Member 6 |
| Database Links | Reactome: R-HSA-2453902 |
| Cellular Localisation | Microsome MembranePeripheral Membrane ProteinLumenal SideEarly Endosome Membrane |
| Alternative Antibody Names | Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 6 antibodyAnti-17-Beta-Hsd 6 antibodyAnti-17-Beta-Hsd6 antibodyAnti-3-Alpha->Beta-Hydroxysteroid Epimerase antibodyAnti-3-Alpha->Beta-Hse antibodyAnti-Oxidative 3-Alpha Hydroxysteroid Dehydrogenase antibodyAnti-Short Chain Dehydrogenase/Reductase Family 9c Member 6 antibodyAnti-HSD17B6 antibodyAnti-RODH antibodyAnti-SDR9C6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
