Anti-HSD17B1 antibody (1-328) (STJ112735)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HSD17B1 (1-328) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSD17B1 |
| Gene ID | 3292 |
| Uniprot ID | DHB1_HUMAN |
| Immunogen Region | 1-328 |
| Immunogen Sequence | MARTVVLITGCSSGIGLHLA VRLASDPSQSFKVYATLRDL KTQGRLWEAARALACPPGSL ETLQLDVRDSKSVAAARERV TEGRVDVLVCNAGLGLLGPL EALGEDAVASVLDVNVVGTV RMLQAFLPDMKRRGSGRVLV TGSVGGLMGLPFNDVYCASK FALEGLCESLAVLLLPFGVH LSLIECGPVHTAFMEKVLGS PEEVLDRTDIHTFHRFYQYL AHSKQVFREAAQNPEEVAE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human HSD17B1 (NP_000404.2). |
Additional Info
| Function | Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 117-Beta-Hsd 120 Alpha-Hydroxysteroid Dehydrogenase20-Alpha-HsdE2dhEstradiol 17-Beta-Dehydrogenase 1Placental 17-Beta-Hydroxysteroid DehydrogenaseShort Chain Dehydrogenase/Reductase Family 28c Member 1 |
| Database Links | Reactome: R-HSA-193144Reactome: R-HSA-2453902 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 1 antibodyAnti-17-Beta-Hsd 1 antibodyAnti-20 Alpha-Hydroxysteroid Dehydrogenase antibodyAnti-20-Alpha-Hsd antibodyAnti-E2dh antibodyAnti-Estradiol 17-Beta-Dehydrogenase 1 antibodyAnti-Placental 17-Beta-Hydroxysteroid Dehydrogenase antibodyAnti-Short Chain Dehydrogenase/Reductase Family 28c Member 1 antibodyAnti-HSD17B1 antibodyAnti-E17KSR antibodyAnti-EDH17B1 antibodyAnti-EDH17B2 antibodyAnti-EDHB17 antibodyAnti-SDR28C1 antibody |
Information sourced from Uniprot.org