| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HS3ST3A1 (44-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HS3ST3A1 |
| Gene ID: |
9955 |
| Uniprot ID: |
HS3SA_HUMAN |
| Immunogen Region: |
44-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 44-140 of human HS3ST3A1 (NP_006033.1). |
| Immunogen Sequence: |
ERCQTLSGPVVGLSGGGEEA GAPGGGVLAGGPRELAVWPA AAQRKRLLQLPQWRRRRPPA PRDDGEEAAWEEESPGLSGG PGGSGAGSTVAEAPPGT |
| Tissue Specificity | Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. |
| Protein Name | Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3a1Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 3a13-Ost-3aHeparan Sulfate 3-O-Sulfotransferase 3a1H3-Ost-3a |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3a1 antibodyAnti-Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 3a1 antibodyAnti-3-Ost-3a antibodyAnti-Heparan Sulfate 3-O-Sulfotransferase 3a1 antibodyAnti-H3-Ost-3a antibodyAnti-HS3ST3A1 antibodyAnti-3OST3A1 antibodyAnti-HS3ST3A antibodyAnti-UNQ2551 antibodyAnti-PRO6180 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
