| Tissue Specificity | Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. |
| Protein Name | Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3a1Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 3a13-Ost-3aHeparan Sulfate 3-O-Sulfotransferase 3a1H3-Ost-3a |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3a1 antibodyAnti-Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 3a1 antibodyAnti-3-Ost-3a antibodyAnti-Heparan Sulfate 3-O-Sulfotransferase 3a1 antibodyAnti-H3-Ost-3a antibodyAnti-HS3ST3A1 antibodyAnti-3OST3A1 antibodyAnti-HS3ST3A antibodyAnti-UNQ2551 antibodyAnti-PRO6180 antibody |
Information sourced from Uniprot.org
