| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-HS3ST1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 35kDa band observed in Human Brain (Cerebellum, Cerebral Cortex, Frontal Cortex) lysates (calculated MW of 35.8kDa according to NP_005105.1). Recommended concentration: 1-3µg/m |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HS3ST1 |
| Gene ID: | 9957 |
| Uniprot ID: | HS3S1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_005105.1 |
| Immunogen Sequence: | NKLHEYFHEPNKK |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. |
| Protein Name | Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 13-Ost-1Heparan Sulfate 3-O-Sulfotransferase 1H3-Ost-1 |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus Lumen |
| Alternative Antibody Names | Anti-Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1 antibodyAnti-Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 1 antibodyAnti-3-Ost-1 antibodyAnti-Heparan Sulfate 3-O-Sulfotransferase 1 antibodyAnti-H3-Ost-1 antibodyAnti-HS3ST1 antibodyAnti-3OST antibodyAnti-3OST1 antibody |
Information sourced from Uniprot.org