| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Heparan sulfate glucosamine 3-O-sulfotransferase 1 (201-251 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HS3ST1 |
| Gene ID: |
9957 |
| Uniprot ID: |
HS3S1_HUMAN |
| Immunogen Region: |
201-251 aa |
| Specificity: |
This antibody detects endogenous levels of human HS3S1 |
| Immunogen: |
Synthesized peptide derived from the human HS3S1 at the amino acid range 201-251 |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. |
| Protein Name | Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 13-Ost-1Heparan Sulfate 3-O-Sulfotransferase 1H3-Ost-1 |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus Lumen |
| Alternative Antibody Names | Anti-Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1 antibodyAnti-Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 1 antibodyAnti-3-Ost-1 antibodyAnti-Heparan Sulfate 3-O-Sulfotransferase 1 antibodyAnti-H3-Ost-1 antibodyAnti-HS3ST1 antibodyAnti-3OST antibodyAnti-3OST1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
