| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HRH4 (194-304) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HRH4 |
| Gene ID: |
59340 |
| Uniprot ID: |
HRH4_HUMAN |
| Immunogen Region: |
194-304 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 194-304 of human HRH4 (NP_067637.2). |
| Immunogen Sequence: |
NMNIYWSLWKRDHLSRCQSH PGLTAVSSNICGHSFRGRLS SRRSLSASTEVPASFHSERQ RRKSSLMFSSRTKMNSNTIA SKMGSFSQSDSVALHQREHV ELLRARRLAKS |
| Tissue Specificity | Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. |
| Function | The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). |
| Protein Name | Histamine H4 ReceptorH4rHh4rAxor35G-Protein Coupled Receptor 105Gprv53Pfi-013Sp9144 |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H4 Receptor antibodyAnti-H4r antibodyAnti-Hh4r antibodyAnti-Axor35 antibodyAnti-G-Protein Coupled Receptor 105 antibodyAnti-Gprv53 antibodyAnti-Pfi-013 antibodyAnti-Sp9144 antibodyAnti-HRH4 antibodyAnti-GPCR105 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
