Anti-HRASLS2 antibody (Internal) (STJ71604)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HRASLS2 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx. 21kDa band in Human Kidney lysates after 0.5 µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PLAAT2 |
| Gene ID | 54979 |
| Uniprot ID | PLAT2_HUMAN |
| Accession Number | NP_060348.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QELPYSLTSDNC |
| Specificity | This design was based on provisional sequence data. |
Additional Info
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Exhibits high phospholipase A1/2 activity and low N-acyltransferase activity. |
| Protein Name | Phospholipase A And Acyltransferase 2 Hras-Like Suppressor 2 |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | CytoplasmMembraneSingle-Pass Membrane ProteinExhibits A Granular Pattern In The Cytoplasm With Preferential Perinuclear Localization |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 2 antibodyAnti-Hras-Like Suppressor 2 antibodyAnti-PLAAT2 antibodyAnti-HRASLS2 antibody |
Information sourced from Uniprot.org