| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HPX |
| Gene ID: | 3263 |
| Uniprot ID: | HEMO_HUMAN |
| Immunogen Region: | 363-462 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 363-462 of human Hemopexin (HPX) (P02790). |
| Immunogen Sequence: | AFICPGSSRLHIMAGRRLWW LDLKSGAQATWTELPWPHEK VDGALCMEKSLGPNSCSANG PGLYLIHGPNLYCYSDVEKL NAAKALPQPQNVTSLLGCTH |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
| Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
| Protein Name | HemopexinBeta-1b-Glycoprotein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Hemopexin antibodyAnti-Beta-1b-Glycoprotein antibodyAnti-HPX antibody |
Information sourced from Uniprot.org