Anti-HPS6 antibody (168-218 aa) (STJ196054)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HPS6 at the amino acid range 168-218
General Information
| Short Description | Rabbit polyclonal anti-BLOC-2 complex member HPS6 (168-218 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HPS6 |
| Gene ID | 79803 |
| Uniprot ID | HPS6_HUMAN |
| Immunogen | Synthesized peptide derived from the human HPS6 at the amino acid range 168-218 |
| Immunogen Region | 168-218 aa |
| Specificity | This antibody detects endogenous levels of HPS6 at Human/Mouse/Rat |
Additional Info
| Function | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. |
| Protein Name | Bloc-2 Complex Member Hps6Hermansky-Pudlak Syndrome 6 ProteinRuby-Eye Protein HomologRu |
| Database Links | |
| Cellular Localisation | Microsome MembraneCytoplasmCytosolEarly Endosome MembraneLysosome Membrane |
| Alternative Antibody Names | Anti-Bloc-2 Complex Member Hps6 antibodyAnti-Hermansky-Pudlak Syndrome 6 Protein antibodyAnti-Ruby-Eye Protein Homolog antibodyAnti-Ru antibodyAnti-HPS6 antibody |
Information sourced from Uniprot.org