| Host: | Goat |
| Applications: | Pep-ELISA/IF/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Hornerin (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.IF: Strong expression of the protein seen in the cytoplasm and plasma membrane of U251 cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of A549 cells. Recommended c |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HRNR |
| Gene ID: | 388697 |
| Uniprot ID: | HORN_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001009931.1 |
| Immunogen Sequence: | QYATQHGEYDTLNK |
| Post Translational Modifications | Processed during the process of epidermal differentiation. Forms covalent cross-links mediated by transglutaminase TGM3, between glutamine and the epsilon-amino group of lysine residues (in vitro). |
| Function | Component of the epidermal cornified cell envelopes. |
| Protein Name | Hornerin |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleFound In Keratohyalin Granules In The Granular Cells Of The Epidermis |
| Alternative Antibody Names | Anti-Hornerin antibodyAnti-HRNR antibodyAnti-S100A18 antibody |
Information sourced from Uniprot.org