Host: |
Rabbit |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-HNRNPH1 (191-449) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HNRNPH1 |
Gene ID: |
3187 |
Uniprot ID: |
HNRH1_HUMAN |
Immunogen Region: |
191-449 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 191-449 of human HNRNPH1 (NP_005511.1). |
Immunogen Sequence: |
VRTHYDPPRKLMAMQRPGPY DRPGAGRGYNSIGRGAGFER MRRGAYGGGYGGYDDYNGYN DGYGFGSDRFGRDLNYCFSG MSDHRYGDGGSTFQSTTGHC VHMRGLPYRATENDIYNFFS PLNPVRVHIEIGPDGRVTGE ADVEFATHEDAVAAMSKDKA NMQHRYVELFLNSTAGASGG AYEHRYVELFLNSTAGASGG AYGSQMMGGMGLSNQSSYGG PASQQLSGGYGGGYGGQSS |
Tissue Specificity | Expressed ubiquitously. |
Function | This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). |
Protein Name | Heterogeneous Nuclear Ribonucleoprotein HHnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed |
Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203 |
Cellular Localisation | NucleusNucleoplasm |
Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein H antibodyAnti-Hnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed antibodyAnti-HNRNPH1 antibodyAnti-HNRPH antibodyAnti-HNRPH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance