Anti-DMKN antibody (355-449) (STJ115810)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DMKN (355-449) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DMKN |
| Gene ID | 93099 |
| Uniprot ID | DMKN_HUMAN |
| Immunogen Region | 355-449 |
| Immunogen Sequence | WEDFKQNTPFLNWKAIIEGA DASSLQKRAGRADQPGAGWQ EVAAVTSKNYNYNQHAYPTA YGGKYSVKTPAKGGVSPSSS ASRVQPGLLQWVKFW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 355-449 of human DMKN (NP_001177276.1). |
Additional Info
| Tissue Specificity | Expressed in epidermis.in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expressed in epidermis. |
| Post Translational Modifications | O-glycosylated. |
| Function | May act as a soluble regulator of keratinocyte differentiation. |
| Protein Name | DermokineEpidermis-Specific Secreted Protein Sk30/Sk89 |
| Database Links | Reactome: R-HSA-9725554 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Dermokine antibodyAnti-Epidermis-Specific Secreted Protein Sk30/Sk89 antibodyAnti-DMKN antibodyAnti-UNQ729 antibodyAnti-PRO1411 antibody |
Information sourced from Uniprot.org