| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPH1 |
| Gene ID: | 3187 |
| Uniprot ID: | HNRH1_HUMAN |
| Immunogen Region: | 191-449 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 191-449 of human HNRNPH1 (NP_005511.1). |
| Immunogen Sequence: | VRTHYDPPRKLMAMQRPGPY DRPGAGRGYNSIGRGAGFER MRRGAYGGGYGGYDDYNGYN DGYGFGSDRFGRDLNYCFSG MSDHRYGDGGSTFQSTTGHC VHMRGLPYRATENDIYNFFS PLNPVRVHIEIGPDGRVTGE ADVEFATHEDAVAAMSKDKA NMQHRYVELFLNSTAGASGG AYEHRYVELFLNSTAGASGG AYGSQMMGGMGLSNQSSYGG PASQQLSGGYGGGYGGQSS |
| Tissue Specificity | Expressed ubiquitously. |
| Function | This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein HHnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein H antibodyAnti-Hnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed antibodyAnti-HNRNPH1 antibodyAnti-HNRPH antibodyAnti-HNRPH1 antibody |
Information sourced from Uniprot.org