Anti-HNRNPF antibody (1-280) (STJ27456)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HNRNPF (1-280) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HNRNPF |
| Gene ID | 3185 |
| Uniprot ID | HNRPF_HUMAN |
| Immunogen Region | 1-280 |
| Immunogen Sequence | MMLGPEGGEGFVVKLRGLPW SCSVEDVQNFLSDCTIHDGA AGVHFIYTREGRQSGEAFVE LGSEDDVKMALKKDRESMGH RYIEVFKSHRTEMDWVLKHS GPNSADSANDGFVRLRGLPF GCTKEEIVQFFSGLEIVPNG ITLPVDPEGKITGEAFVQFA SQELAEKALGKHKERIGHRY IEVFKSSQEEVRSYSDPPLK FMSVQRPGPYDRPGTARRYI GIVKQAGLERMRPGAYSTG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HNRNPF (NP_001091678.1). |
Additional Info
| Tissue Specificity | Expressed ubiquitously. |
| Post Translational Modifications | Sumoylated. |
| Function | Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein FHnrnp FNucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203Reactome: R-HSA-8950505 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein F antibodyAnti-Hnrnp F antibodyAnti-Nucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed antibodyAnti-HNRNPF antibodyAnti-HNRPF antibody |
Information sourced from Uniprot.org