| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPF |
| Gene ID: | 3185 |
| Uniprot ID: | HNRPF_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HNRNPF (NP_001091678.1). |
| Immunogen Sequence: | MMLGPEGGEGFVVKLRGLPW SCSVEDVQNFLSDCTIHDGA AGVHFIYTREGRQSGEAFVE LGSEDDVKMALKKDRESMGH RYIEVFKSHRTEMDWVLKHS GPNSADSANDGFVRLRGLPF GCTKEEIVQFFSGLEIVPNG ITLPVDPEGKITGEAFVQFA SQELAEKALGKHKERIGHRY IEVFKSSQEEVRSYSDPPLK FMSVQRPGPYDRPGTARRYI GIVKQAGLERMRPGAYSTG |
| Tissue Specificity | Expressed ubiquitously. |
| Post Translational Modifications | Sumoylated. |
| Function | Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein FHnrnp FNucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203Reactome: R-HSA-8950505 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein F antibodyAnti-Hnrnp F antibodyAnti-Nucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed antibodyAnti-HNRNPF antibodyAnti-HNRPF antibody |
Information sourced from Uniprot.org