Anti-HNRNPA0 antibody (1-180) (STJ27825)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HNRNPA0 (1-180) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HNRNPA0 |
| Gene ID | 10949 |
| Uniprot ID | ROA0_HUMAN |
| Immunogen Region | 1-180 |
| Immunogen Sequence | MENSQLCKLFIGGLNVQTSE SGLRGHFEAFGTLTDCVVVV NPQTKRSRCFGFVTYSNVEE ADAAMAASPHAVDGNTVELK RAVSREDSARPGAHAKVKKL FVGGLKGDVAEGDLIEHFSQ FGTVEKAEIIADKQSGKKRG FGFVYFQNHDAADKAAVVKF HPIQGHRVEVKKAVPKEDIY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HNRNPA0 (NP_006796.1). |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA. Arg-291 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A0Hnrnp A0 |
| Database Links | |
| Cellular Localisation | NucleusComponent Of Ribonucleosomes |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A0 antibodyAnti-Hnrnp A0 antibodyAnti-HNRNPA0 antibodyAnti-HNRPA0 antibody |
Information sourced from Uniprot.org